A.G.E. Interrupter Advanced 120ML PRO SIZE

$427.07 $363.01 SAVE 15%
Add to Wishlist

visamasteramazon paymentsamerican expressapple paypaypal
Dermatology Details

Product Overview

SkinCeuticals A.G.E. Interrupter Advanced is a breakthrough anti-wrinkle cream backed by 15+ years of glycation research, clinically proven to reverse skin-aging glycation by up to 33% and reduce wrinkles in 5 facial zones.

Glycation is a major factor of skin aging that occurs when excess sugars bind to collagen and elastin, forming Advanced Glycation End-products (A.G.E.s). These A.G.E.s weaken collagen, leading to wrinkles, loss of firmness, and a dull complexion. A.G.E. Interrupter Advanced addresses all phases of the glycation process, including UV-induced glycation.

This next-generation formula features 18% concentrated Proxylane™ (20% higher activity than the original), 4.25% wild fruit flavonoids (12.5% higher activity), and 0.1% glycyrrhetinic acid. The result is a potent anti-aging moisturizer that smooths visible lines, reduces discoloration, and restores skin density with a luxurious, satin finish.


Key Features

Reverses Glycation by 33%: Clinically proven to help reverse the skin-aging glycation process that weakens collagen and causes wrinkles

Targets 5 Wrinkle Zones: Reduces forehead wrinkles, nasolabial folds, marionette lines, glabellar wrinkles, and crow's feet

3x Better Lifting with RF Microneedling: Physician-tested to complement radiofrequency microneedling treatments for superior lifting results in 12 weeks

Restores Skin Density: Helps rebuild the skin's structural integrity compromised by glycation

Reduces Visible Discoloration: Promotes a healthier, more even complexion

All-Day Hydration: Delivers rich moisture with a luxurious, satin finish

GLP-1 Patient Tested: Physician-tested for users of GLP-1 medications experiencing accelerated facial aging

Clean Formula: Free of parabens, drying alcohol, and dyes


Specifications

Specification

Details

Brand

SkinCeuticals

Size

120 ml

Product Type

Anti-Wrinkle Face Cream

Key Active Ingredients

18% Proxylane™, 4.25% Wild Fruit Flavonoids, 0.1% Glycyrrhetinic Acid, 3% Hepes, 1% Niacinamide

Skin Types

Dry, Normal, Combination, Sensitive

Concerns

Fine Lines, Deep Wrinkles, Loss of Firmness, Dullness, Discoloration

Texture

Whipped, Creamy-Balm

Formula

Paraben-free, Drying Alcohol-free, Dye-free



Why Choose A.G.E. Interrupter Advanced?

1. 15+ Years of Glycation Research: The most scientifically advanced anti-glycation formula from SkinCeuticals, addressing all phases of the glycation process—including UV-induced glycation

2. Upgraded Next-Gen Formula: Contains 20% higher Proxylane™ activity and 12.5% higher wild fruit flavonoid activity than the original A.G.E. Interrupter

3. Complements Professional Treatments: Physician-tested to enhance RF microneedling results by 3x and reduce skin laxity for GLP-1 patients

4. Multi-Benefit Correction: One cream that addresses wrinkles, firmness, density, discoloration, and hydration

5. Dermatologist Recommended: Backed by board-certified dermatologists like Dr. Sherry Ingraham who recommend it for at-home anti-aging


How to Use

Step 1: Prep + Dispense

Twice daily, scoop a thin, even layer of A.G.E. Interrupter Advanced onto your fingertips.

Step 2: Apply + Complete

Massage onto the entire face, neck, and chest until fully absorbed.


Morning Routine: Cleanser → Vitamin C serum (e.g., C E Ferulic®) → A.G.E. Interrupter Advanced → Sunscreen

Evening Routine: Cleanser → Retinol (optional) → A.G.E. Interrupter Advanced


Pro Tip: A small amount goes a long way—use only a thin layer for best results.


Key Ingredients Explained

Ingredient

Concentration

Function

Proxylane™

18%

Supports skin's integrity, corrects visible signs of aging like wrinkles and laxity

Wild Fruit Flavonoids

4.25%

Blueberry + pomegranate extracts reduce oxidative stress linked to A.G.E. formation

Glycyrrhetinic Acid

0.1%

Counters dull tone linked to A.G.E. accumulation; known for soothing properties

Hepes

3%

Activates natural enzymes to promote cell turnover while hydrating

Niacinamide

1%

Vitamin B3 that soothes and supports skin's moisture barrier



FAQ

Q: What is glycation and why does it cause aging?

A: Glycation occurs when excess sugars bind to collagen and elastin fibers, forming Advanced Glycation End-products (A.G.E.s). These A.G.E.s weaken and stiffen collagen, leading to wrinkles, loss of firmness, and a dull, sallow complexion. Unlike sun damage, glycation is an intrinsic aging process that affects everyone.


Q: How is A.G.E. Interrupter Advanced different from the original?

A: A.G.E. Interrupter Advanced is a next-generation formula that addresses all phases of the glycation process, including UV-induced glycation. It contains 20% higher Proxylane™ activity, 12.5% higher wild fruit flavonoid activity, and a new ingredient—glycyrrhetinic acid—for superior anti-aging results.


Q: What's the difference between A.G.E. Interrupter Advanced and Triple Lipid Restore 2:4:2?

A: A.G.E. Interrupter Advanced targets glycation-related aging (wrinkles, firmness, discoloration). Triple Lipid Restore 2:4:2 addresses lipid loss (facial fullness, rough texture, dullness). They can be used together for comprehensive anti-aging correction.


Q: Can I use A.G.E. Interrupter Advanced with retinol?

A: Yes. Apply retinol first at night, then layer A.G.E. Interrupter Advanced on top once the retinol has absorbed.


Q: When will I see results?

A: Clinical studies showed visible improvements to fine lines and deep wrinkles in 12 weeks of consistent twice-daily use.


Q: Is A.G.E. Interrupter Advanced suitable for GLP-1 medication users?

A: Yes. GLP-1 medications can accelerate facial aging (volume loss, laxity). A.G.E. Interrupter Advanced is physician-tested for GLP-1 patients and, when paired with A.G.E. Interrupter Ultra Serum and lifting ultrasound treatments, reduced skin laxity by 20% vs. control in 12 weeks.


Visible Results (Clinical Data)

Timeline

Results

12 Weeks

Reduction in wrinkles across 5 facial zones

12 Weeks (with RF Microneedling)

3x better lifting results

12 Weeks (GLP-1 + Ultrasound)

20% reduction in skin laxity vs. control



Clinical Improvements at 12 Weeks:

Wrinkle Type

Reduction

Global Fine Lines

14%

Forehead Wrinkles

11.5%

Nasolabial Folds

11%

Marionette Wrinkles

7%

Glabellar Wrinkles

7%

Crow's Feet

7%



GLP-1 User Results (with Ultrasound):

44% reduction in facial laxity

34% reduction in marionette lines

84% of participants reported visibly tighter skin


Understanding Glycation: The Hidden Aging Process


Signs of Glycation:

1. Wrinkling and crepiness - Loss of skin elasticity

2. Loss of firmness - Weakened collagen structure

3. Dull, sallow complexion - A.G.E. accumulation affects skin tone


Glycation Prevention Tips:

DO: Wear broad-spectrum sunscreen daily to protect against UV-induced glycation  

DO: Reduce sugar and alcohol intake—high-sugar diets promote glycation  

DON'T: Expose skin to cigarette smoke, which accelerates glycation

All Duties Included, Guaranteed

Good news for our U.S. customers!

To make shopping with us worry-free, all orders shipped to the United States will have all import duties and taxes fully prepaid by us, with no extra fees at delivery.

On top of that, we continue to offer free shipping on all orders over $99CAD, so you can shop with confidence and ease.

Free Shipping Over CA$99

we continue to offer free shipping on all orders over $99CAD, so you can shop with confidence and ease.

100% Authentic Sourcing

At Treasurescape, we invest in science, not hype. Every product in our curated portfolio is hand-selected from authorized clinical channels to guarantee measurable results. We empower you to achieve professional-grade outcomes with formulas that respect both your skin and your standards.